About MicroRx Infectious Disease Supercluster Personnel COO - Guiles Bus. Dev. Associate - Tompkins General Inquiry Contact Information Advisory Northern Colorado Infectious Disease Research Colorado Bioscience Colorado Bioscience Association Colorado Bioscience Roadmap 2008 Downloadable Documents MicroRx Brochure Infectious Disease Supercluster Featured Research Facilities and Resources Partnering Featured Research Emerging Pathogen Threats Food Safety Mycobacterial Disease Vector-borne Disease Resources Animal Models Product Development and Manufacturing Research Innovation Center Rocky Mountain Regional Center for Excellence Infectious Disease Research Center Start-ups Intellectual Property For Researchers CSU Superclusters Activities MicroRx Cluster Leaders NeoTREX - Cancer Research CENERGY - Clean Energy Technology Transfer Process Legal Agreements CDA's Consulting IDF Hybridoma Development Agreement Contact Us Email Registration General Inquiry

Rocky Mountain Regional Center for Excellence           The RMRCE comprises 18 institutions in Colorado, Utah, Wyoming, Montana, North Dakota, and South Dakota that have combined resources to address the national need for an improved scientific infrastructure and development of novel diagnostic, therapeutic and vaccine countermeasures against Category A, B, and C pathogens. Three scientific cores provide access to state-of-the-art proteomics, standardized small animal and aerosol models of disease transmission, and BSL3 laboratory facilities for translational development of vaccines and drugs leading to FDA approval. A wealth of scientific expertise on biothreat agents and contemporary biomedical technology is applied to establishing new products related to biodefense.           RMRCE Specialized Functions           Animal Models   Evaluate exposure routes to pathogens that require specialized containment safeguards     - Aerosol inhalation     - Arthropod-borne transmission     - Direct inoculation (s.c., i.m., i.v., i.t.)   Species diversity     - Mice, rats, hamsters, raccoons, dogs, cats, horses, cattle, aligators, and birds       (sparrows to emus)       Genomics and Proteomics   Customized spotted DNA microarrays     - Mouse, Bukholderia, F. tularensis SCHU14   Affymetrix gene chips   Proteome and protein identification via mass spectrometry and Biacore   Bioinformatics   Outsourcing support for standard services     - DNA sequencing, custom peptides, etc.       Product Development and Manufacturing   GLP and cGMP production of reagents   Full or collaborative Development and Manufacturing service   Pre-IND Regulatory Guidance   BSL-2 and BSL-3 containment manufacturing of biologics in 3900 sq ft space     - CDC Category A-C Select Agents   Product hold, inventory, and long-term storage     - cGMP-compliant vaporized LN2       Biodefense Training   Train-the-Trainer programs     - Zoonotic diseases, general     - Avian flu     - Bovine spongiform encephalopathy (BSE)

Copyright © 2007 MicroRx. All rights reserved.