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Vector-borne Diseases |
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30 faculty and research staff |
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$5 million in annual research funding |
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Arthropod-borne pathogens and diseases: Dengue virus, yellow fever, phlebovirus, Sindbis virus, West Nile virus, Japanese encephalitis virus, Venezuela equine encephalitis virus, western equine encephalitis virus, St. Louis encephalitis virus, La Crosse encephalitis virus, chikungunya virus, O’nyong-nyong virus; plague, Lyme disease, tularemia; malaria, leishmaniasis |
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Rodent-borne pathogens: Hantavirus |
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As West Nile and Chikungunya viruses emerge in new areas and dengue and yellow fever resurge throughout the tropics, developing new vaccines, therapeutics, diagnostics and control measures are critical.
Such vector- or arthropod- (mosquitoes, fleas and ticks) borne infectious diseases exact a heavy toll on human and animal health and impede social and economic development in many parts of the
world. More than 2.5 billion people are at risk for dengue virus infection; 50 million cases of dengue are estimated to occur annually, and ominously, the incidence of dengue hemorrhagic fever is rapidly increasing throughout the tropics.
The public health importance of vector-borne diseases is staggering and on a par with HIV and TB. |
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Grappling with this issue is Colorado State University’s Arthropod-borne Infectious Disease Laboratory
(AIDL). Located on the Foothills Research Campus, the multi-user facility has state of the art
BSL-2 and BSL-3 insectaries and containment laboratories for faculty to conduct experiments involving
various vectors and vector-borne pathogens. New Interventions, vaccines & Therapeutics are being
developed to control dengue, malaria, leishmaniasis, and other vector-borne diseases throughout
the world. Researchers at AIDL also study hantavirus maintenance and transmission among rodent
populations at specific sites in Colorado, and collaborate with local laboratories of the Centers for
Disease Control and Prevention and the U.S. Department of Agriculture. |
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Major Research Initiatives |
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Molecular approaches to understand mechanisms of vector-pathogen-host interactions |
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Development of new vaccines, therapeutics, and rapid clinical and field relevant diagnostic assays |
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Determine effects of genetic diversity of vectors, viruses and hosts on viral persistence and emergence |
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Vector-pathogen surveillance and control |
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Pathogenesis of vector-borne disease in animal models |
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Development of decision support systems and mosquito control measures for malaria and dengue |
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More information on this program is available here. |
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